Insulin is an important hormone that regulates nutrient uptake into cells, such as muscle. For weightlifters, carbohydrate and amino acid uptake dictates how the body is able to fuel and grow muscles. Muscle growth can be limited by amino acid availability, and limited carbohydrate availability can cause the muscle to cannibalize itself to convert amino acids into a fuel source – carbohydrate. Therefore, it is imperative that weightlifters keep their insulin levels optimized to ensure transport and delivery of essential nutrients. To address these needs, Performax Labs’ brings you SlinMaxTM, a precision formula to maximize nutrient partitioning – nutrient delivery to muscles for fuel rather than fat cells for storage. This combination of research-backed biomolecules improves insulin action via multiple mechanisms, thereby utilizing a synergistic approach to nutrient partitioning.
• Na-R-ALA – A stable form of alpha lipoic acid, which increases both insulin action and blood flow, for improved nutrient delivery.
• Agmatine sulfate – Enhances insulin action without affecting insulin levels to act synergistically with insulin enhancers.
• Berberine HCl – Improves insulin sensitivity and nutrient repartitioning as well as some pharmaceuticals.
• Banaba extract – Increases carbohydrate delivery while simultaneously shrinking fat cells.
• Trigonella Seed Isolate – Studies have shown improved insulin action and increased glycogen replenishment after Trigonella seed consumption.
SlinMaxTM has been precisely formulated to increase insulin and to improve its action via independent mechanisms. Therefore, instead of the ingredients competing with each other, they are working together synergistically to maximize the benefits that insulin can provide to your diet and workout regimen. Unlock the power of insulin with the science-backed, efficaciously dosed formula: SlinMaxTM!
R-alpha-lipoic acid is the R isomer, which is the isomer preferred by the body, so it is more bioavailable. The Na or sodium bound to it allows the compound to remain through the absorption process, which also will improve its bioactivity. Alpha-lipoic acid can benefit by both increasing blood flow and nutrient repartitioning. As blood flow increases and more nutrients are delivered, Na-R-ALA will also keep the body in an anabolic state by downregulating AMP kinase, a “starvation” enzyme, and increasing insulin action.
• Numerous studies, such as Gupte et al. (2009), showed that alpha-lipoic acid can lower blood glucose and improve insulin action, thereby improving carbohydrate delivery to muscle tissue.
• Other studies have shown that alpha-lipoic acid can improve blood flow, thereby increasing nutrient delivery.
• Kim et al. (2004) reported that alpha-lipoic acid reduced AMP kinase, a sensor of low nutrient availability. Therefore, alpha-lipoic acid can increase nutrient delivery and storage by reducing AMP kinase.
Agmatine is well known for enhancing blood flow, but it is also a powerful neurotransmitter that acts on multiple receptors. Importantly, it activates imidazoline receptors in the adrenal glands, which will lower blood glucose and increases beta-endorphin. Beta-endorphin will then increase glucose uptake into skeletal muscle via GLUT4 recruitment independent of insulin, such that agmatine enhances the action of insulin without affecting insulin levels.
• Evans et al. (1997) showed that glucose uptake into skeletal muscle from agmatine sulfate administration occurs both during exercise and at rest.
Berberine is a potent stimulator of nutrient partitioning and glucose transport, and is as effective as many pharmaceuticals that are used to improve insulin sensitivity and blood glucose.
• A meta-analysis (Dong et al., 2012) demonstrated that berberine induces significant benefits on carbohydrate and fat transport and delivery.
• Yan et al. (2015) showed that berberine can significantly improve insulin sensitivity and lower blood lipids more effectively than pioglitazone (a PPAR activator), indicating powerful nutrient repartitioning.
• Other studies (Zhang et al. 2008) supported the results discussed above regarding berberine’s remarkable effects on insulin and glucose.
Banaba Extract (2% Corosolic Acid)
Banaba extract can improve nutrient repartitioning via multiple mechanisms. Carbohydrate uptake into cells is vastly improved while lipid metabolism is regulated such that fat cells shrink simultaneously.
• Corosolic acid can decrease blood sugar within 60 minutes and can reduce fat in the blood, demonstrating its effectiveness at improving nutrient delivery (Miura et al., 2012).
• Judy and colleagues (2003) demonstrated that Banaba extract for two weeks dropped blood glucose by 30%
• Lagerstroemin, an ellagitannin from Banaba leaf (Hattori et al., 2003), induced insulin-like actions by a mechanism different from insulin, which would lead to synergistic benefits with insulin and other compounds, such as agmatine sulfate.
Cinnamon Bark Extract
Cinnamon is well known for its effects on blood glucose and nutrient delivery. Cinnamon increases the activity of endogenous insulin while also acting as an insulin mimetic to synergistically activate glucose transport.
• Broadhurst et al. (2000) demonstrated a 20-fold increase in insulin action with cinnamon extract.
• Multiple studies confirm the ability of cinnamon extract to act as an insulin mimetic.
Trigonella Seed Isolate (40% 4-hydroxyisoleucine)
Trigonella seed, commonly known as fenugreek, has a history of culinary and medicinal use, mostly for improving blood glucose. Both insulin action and muscle glycogen replenishment have been demonstrated in studies.
• Abdel-Barry et al. (2009) observed that fenugreek significantly lowered blood glucose by 13.4% in healthy, young men.
• Gupta et al. (2001) demonstrated that fenugreek improves insulin action and improves blood lipid profiles, which together indicates improved nutrient partitioning.
• Ruby et al. (2005) showed that post-exercise rates of glycogen resynthesis are increased by 63% in trained cyclists, illustrating that fenugreek improves glucose uptake and conversion to muscle glycogen.
Black Pepper Extract (95% Piperine)
Piperine inhibits cytochrome P450 enzymes, which play essential roles in the elimination of many compounds. Therefore, piperine can increase the time that certain compounds stay in the bloodstream, thereby improving their effectiveness. This is especially important for compounds that the body metabolizes quickly, such as ecdysteroids.
Chromium is an essential trace mineral that is required by the body for multiple functions. One of its purposes is to help regulate blood glucose.
• In a meta-analysis, Abdollahi et al. (2013) showed that multiple studies support the effects of chromium supplementation on the reduction of blood glucose, which translates to greater glucose delivery to skeletal muscle.
• in a study by Kim et al. (1997), chromium picolinate improved insulin sensitivity.
• Anderson et al. (1997) demonstrated that chromium can improve both carbohydrate and fatty acid transport into muscle tissue.
Q: How do I take Performax Labs’ SlinMax?
A: Take one serving daily, preferably with your highest carbohydrate meal.
Q: What other Performax Labs’ products can I stack with SlinMax?
A: To optimize your bulk, try our Bulk stack which combines SlinMax with AlphaMax, MassMax, and IntraMax for total hormonal optimization and performance.
Q: Don’t carbs make you fat?
A: If obesity is an issue, then carbohydrates should be monitored appropriately. For weightlifters, however, carbs provide the main fuel (glycogen) for muscles and promote delivery of amino acids for muscle growth, so they are important for gains.
Q: When is the best time to take Performax Labs’ SlinMax?
A: Before your high carb meal is best, so usually either lunch or dinner, depending on your diet.
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Banaba Extract (2% Corosolic Acid)
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2. Hattori, K., et al., Activation of insulin receptors by lagerstroemin. J Pharmacol Sci, 2003. 93(1): p. 69-73.
3. Judy, W.V., et al., Antidiabetic activity of a standardized extract (Glucosol) from Lagerstroemia speciosa leaves in Type II diabetics. A dose-dependence study. J Ethnopharmacol, 2003. 87(1): p. 115-7.
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Trigonella Seed Isolate (40% 4-hydroxyisoleucine)
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Black Pepper Extract (95% Piperine)
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2. Rao, V.R., et al., Simultaneous determination of bioactive compounds in Piper nigrum L. and a species comparison study using HPLC-PDA. Nat Prod Res, 2011. 25(13): p. 1288-94.
3. Shoba, G., et al., Influence of piperine on the pharmacokinetics of curcumin in animals and human volunteers. Planta Med, 1998. 64(4): p. 353-6.
4. Han, H.K., The effects of black pepper on the intestinal absorption and hepatic metabolism of drugs. Expert Opin Drug Metab Toxicol, 2011. 7(6): p. 721-9.
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2. Kim, D.-S., et al., Effects of chromium picolinate supplementation on insulin sensitivity, serum lipids, and body weight in dexamethasone-treated rats. Metabolism, 2002. 51(5): p. 589-594.
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