These are the FAQ's and Science behind our flagship formulations
Take one serving before each workout. VasoMax is efficaciously dosed, which means that one serving will do the trick, but it is safe enough to be taken more than once per day, such as for multiple daily workouts.
Blood is the transportation system of the body. To effectively deliver oxygen and nutrients to the muscles and remove waste products, proper blood flow is needed. During exercise, there is more demand for oxygen and nutrients, and the body naturally produces free radicals and inflammatory mediators since exercise is “stressful.” Vasodilation can improve this transport.
VasoMax stacks amazingly well with HyperMax XT to give you the stimulant plus pump combo – our PWO Stack – or can be combined with Nootropimax and IntraMax for our Low Stim Stack.
The best time is 20-30 minutes before your workout to give the molecules time to be absorbed and to stimulate blood flow. There are no stimulants in this product, so it can be effectively taken morning, noon, and night.
In this section we will cover each and every ingredient
GlycerPump is a patented, super-concentrated form of glycerol, which is an osmolyte that will improve hydration via increased intracellular uptake into the muscle. The resultant swelling of the muscle will also stimulate satellite cell recruitment, resulting in muscle growth.
A recent meta-analysis by Goulet et al. (2007) concluded that hyper-hydration with glycerol enhances prolonged exercise performance under hot conditions.
Alpha-GPC is the most that is highly bioavailable source of choline on the market. It also traverses the blood-brain barrier, such that it increases acetylcholine in the brain and can therefore enhance cognitive function and neuronal health. Its non-choline metabolite – glycerophosphate – can improve membrane structure and function.
Increased growth hormone and upper body power output were observed after supplementation with alpha-GPC.
This traditional herb has been used for stress relief for centuries. By inhibiting both serotonin and phosphodiesterase 4, it is able to improve cognition, mood, and blood flow.
Terburg et al. (2013) showed a reduction in state anxiety after administration of Sceletium tortuosum is response to a cognitive task
Chiu and colleagues (2014) demonstrated that consuming Sceletium tortuosum improved executive function and cognitive flexibility: two cognitive domains necessary for athletic performance.
Huperzine A is an acetylcholinesterase inhibitor, which is an enzyme that breaks down acetylcholine. Through this process, huperzine A increases acetylcholine – the “learning” neurotransmitter that is also responsible for muscular contraction.
Zhao et al. (2003) showed the potent ability of huperzine A to inhibit acetylcholinesterase in the cerebral cortex, hippocampus, and striatum.
These are the references to the exact studies, down the page we have created these formulations around.
Ross, M.L., et al., Effects of lowering body temperature via hyperhydration, with and without glycerol ingestion and practical precooling on cycling time trial performance in hot and humid conditions. Journal of the International Society of Sports Nutrition, 2012. 9(1): p. 55.
Nelson, J.L. and R.A. Robergs, Exploring the potential ergogenic effects of glycerol hyperhydration. Sports medicine, 2007. 37(11): p. 981-1000.
Freund, B.J., et al., Glycerol hyperhydration: hormonal, renal, and vascular fluid responses. J Appl Physiol (1985), 1995. 79(6): p. 2069-77.
Koenigsberg, P.S., et al., Sustained hyperhydration with glycerol ingestion. Life sciences, 1995. 57(7): p. 645-653.
Hitchins, S., et al., Glycerol hyperhydration improves cycle time trial performance in hot humid conditions. European journal of applied physiology and occupational physiology, 1999. 80(5): p. 494-501.
Johnson, V., A. Carlson, and A. Johnson, Studies on the physiological action of glycerol on the animal organism. American Journal of Physiology–Legacy Content, 1933. 103(3): p. 517-534.
Goulet, E.D., et al., A meta-analysis of the effects of glycerol-induced hyperhydration on fluid retention and endurance performance. International journal of sport nutrition and exercise metabolism, 2007. 17(4): p. 391-410.
De Jesus Moreno Moreno, M., Cognitive improvement in mild to moderate Alzheimer’s dementia after treatment with the acetylcholine precursor choline alfoscerate: a multicenter, double-blind, randomized, placebo-controlled trial. Clin Ther, 2003. 25(1): p. 178-93.
Ziegenfuss, T., J. Landis, and J. Hofheins, Acute supplementation with alpha-glycerylphosphorylcholine augments growth hormone response to, and peak force production during, resistance exercise. Journal of the International Society of Sports Nutrition, 2008. 5(S1): p. P15.
Kawamura, T., et al., Glycerophosphocholine enhances growth hormone secretion and fat oxidation in young adults. Nutrition, 2012. 28(11-12): p. 1122-6.
Troesch, B., et al., Optimization of a phytase-containing micronutrient powder with low amounts of highly bioavailable iron for in-home fortification of complementary foods. Am J Clin Nutr, 2009. 89(2): p. 539-44.
Terburg, D., et al., Acute effects of Sceletium tortuosum (Zembrin), a dual 5-HT reuptake and PDE4 inhibitor, in the human amygdala and its connection to the hypothalamus. Neuropsychopharmacology, 2013. 38(13): p. 2708-16.
Chiu, S., et al., Proof-of-Concept Randomized Controlled Study of Cognition Effects of the Proprietary Extract Sceletium tortuosum (Zembrin) Targeting Phosphodiesterase-4 in Cognitively Healthy Subjects: Implications for Alzheimer’s Dementia. Evid Based Complement Alternat Med, 2014. 2014: p. 682014.
Nell, H., et al., A randomized, double-blind, parallel-group, placebo-controlled trial of Extract Sceletium tortuosum (Zembrin) in healthy adults. J Altern Complement Med, 2013. 19(11): p. 898-904.
Zhao, Q. and X.C. Tang, Effects of huperzine A on acetylcholinesterase isoforms in vitro: comparison with tacrine, donepezil, rivastigmine and physostigmine. European journal of pharmacology, 2002. 455(2): p. 101-107.
Kozikowski, A.P. and W. Tueckmantel, Chemistry, pharmacology, and clinical efficacy of the Chinese nootropic agent huperzine A. Accounts of chemical research, 1999. 32(8): p. 641-650.
Bai, D., Development of huperzine A and B for treatment of Alzheimer’s disease. Pure and applied chemistry, 2007. 79(4): p. 469-479.
Ved, H.S., et al., Huperzine A, a potential therapeutic agent for dementia, reduces neuronal cell death caused by glutamate. Neuroreport, 1997. 8(4): p. 963-967.
Peng, Y., et al., Huperzine A regulates amyloid precursor protein processing via protein kinase C and mitogen-activated protein kinase pathways in neuroblastoma SK-N-SH cells over-expressing wild type human amyloid precursor protein 695. Neuroscience, 2007. 150(2): p. 386-395.
Taddei, S., et al., Vitamin C improves endothelium-dependent vasodilation by restoring nitric oxide activity in essential hypertension. Circulation, 1998. 97(22): p. 2222-2229.
d’Uscio, L.V., et al., Long-term vitamin C treatment increases vascular tetrahydrobiopterin levels and nitric oxide synthase activity. Circulation research, 2003. 92(1): p. 88-95.
Ting, H.H., et al., Vitamin C improves endothelium-dependent vasodilation in patients with non-insulin-dependent diabetes mellitus. Journal of Clinical Investigation, 1996. 97(1): p. 22.
Huang, A., et al., Ascorbic acid enhances endothelial nitric-oxide synthase activity by increasing intracellular tetrahydrobiopterin. Journal of biological chemistry, 2000. 275(23): p. 17399-17406.